Prediction of Inspiratory Effort Response to High PEEP in Patients Recovering From ARDS
Recruiting
Observational Study
Acute Respiratory Distress Syndrome
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 30 (estimated)
- Sponsor
- Sanatorio Anchorena San Martin · Other
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About This Trial
Spontaneous breathing during the transition from controlled to assisted ventilation in ARDS may be harmful, as high respiratory drive can generate large transpulmonary pressure swings and worsen lung injury. Higher PEEP may mitigate this by reducing inspiratory effort and lung stress, but patient response is variable and difficult to predict. While improved lung compliance appears to mediate the p…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Need of invasive mechanical ventilation
* Patients who had fulfill ARDS criteria based on Berlin definition during any time of invasive mechanical ventilation.
* Patient ventilated in pressure support ventilation.
* Time of invasive ventilation expected to be longer than 24 hs…
Contacts