Added Value of Vein of Marshal Ethanol Infusion Compared to Superior Vena Cava Isolation Alone in Patients Undergoing Repeat Ablation for Recurrent Paroxysmal Atrial Fibrillation Despite Durable PV Isolation

Recruiting N/A Interventional Study
Paroxysmal Atrial Fibrillation
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
100 (estimated)
Sponsor
AZ Sint-Jan AV · Other
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About This Trial
The superior vena cava (SVC) is one of the most common non pulmonary vein (PV)-triggers for atrial tachyarrhythmias. SVC electrical isolation can be reached by circular radiofrequency (RF)-ablation under close monitoring of the phrenic nerve. However, adding substrate modification and vein of Marshal (VoM) ethanol infusion to the ablation procedure might substantially improve long-term outcomes. …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients older than 18 years * Patients scheduled for a repeat ablation of PAF after a previous PVI * Confirmation of lasting pulmonary vein isolation at the time of randomization Exclusion Criteria: * Patients with persistent atrial fibrillation * Previous ablation with iso…
Contacts

Michelle Lycke, MSc, PhD

+32 50 45 32 93

michelle.lycke@azsintjan.be

CONTACT