Early Detection of Prostate Cancer

Inclusion Criteria Patient : * Men over 40 being suspicious of prostate cancer * Subject with PSA ≥ 4 and designated for biopsy * Subjects must be able to attend all scheduled visits and to comply with all trial procedures * mpMRI done before prostate biopsy * Subject must be covered by public health insurance * Signed informed consent form Inclusion Criteria Subject Control Patient patient free from prostatic disease : * Men over 40 with no suspicion of prostate cancer * Subject with PSA \< 2.5 and normal digital rectal examination * Subject must be covered by public health insurance * Signed informed consent form Exclusion Criteria Patient : * Subject with histologically confirmed prostate cancer * Subject with a verified viral infection (HIV or Hepatitis) * Subject under Finasteride treatment * Subject under hormonal treatment (analogs, antagonists, androgenics) * Subject with other cancer diagnosed * Subject unable to sign consent * Planned longer stay outside the region that prevents compliance with the visit plan * Subject deprived of liberty, protected adults or vulnerable persons * Urinary infection ≤ 2 months * Subject excluding health insurance registration * Subject refusing to perform prostate biopsy * Subject who are in a dependency or employment with the sponsor or the investigator Exclusion Criteria Subject Control : * Subject with histologically confirmed prostate cancer * Subject with a verified viral infection (HIV or Hepatitis) * Subject under Finasteride treatment * Subject with other cancer diagnosed * Subject unable to sign consent * Planned longer stay outside the region that prevents compliance with the visit plan * Subject deprived of liberty, protected adults or vulnerable persons * Urinary infection ≤ 2 months * Subject excluding health insurance registration