Epidermal Skin Grafts to Improve Healing In Radiation Wounds

Inclusion Criteria: * Status post radiation treatment, with radiation-induced wound. This includes patient with moist desquamation as well as full epidermal necrosis and superficial dermal ulcerations, this wound would otherwise be allowed to heal by secondary intention; * Having suitable areas of treatment: All wounds in the area of interest must be at least 20 cm2 (\~10 cm2 per treatment/control area); * The radiation injury must have a suitable adjacent irradiated control site before initiation of treatment. This will be determined by objective measurements of % wound epithelization, wound erythema, pliability, induration and thickness at enrollment; * Able and willing to comply with all visit, treatment and evaluation schedules and requirements; * Wound considered appropriate by physician to receive epidermal grafting; * Able to understand and provide written informed consent; Exclusion Criteria: * Active tanning, including the use of tanning booths, during the course of the study; * Study wound exhibits clinical signs and symptoms of infection at the screening/enrollment visit; * Patient unable to provide donor site for epidermal harvesting; * Wound sites located on the face, hands or feet * Adverse reactions to compounds of any external agent (e.g., gels, lotions or anesthetic creams) required for use in the study, if no alternative to the said agent exists; * History of collagen vascular disease; * Active Herpes Simplex or Zoster at the time of treatment or having experienced more than three episodes of Herpes Simplex / Zoster eruption within a year of study enrollment; * History of immunosuppression/immune deficiency disorders (including human immunodeficiency virus (HIV) infection or acquired immunodeficiency syndrome (AIDS) or use of immunosuppressive medications; * Significant concurrent illness, such as uncontrolled diabetes (with a hemoglobin A1C of more than 8) (i.e., any disease state that in the opinion of the Investigator would interfere with the anesthesia, treatment, or healing process); * Mentally incompetent, prisoner or evidence of active substance or alcohol abuse; * Any condition which, in the Investigator's opinion, would make it unsafe (for the subject or study personnel) to treat the subject as part of this research study; * Participation in another interventional study with potential exposure to an investigational drug within past 30 days; * Pregnant females, due to possible discomfort with the procedure even though the procedure is localized and there is no new drug.