The objective of this study is to validate 2 multi-contrast sequences, namely the Multi-contrast ATherosclerosis Characterization (MATCH) and Bright-blood and black-blOOd phase SensiTive (BOOST) inversion recovery sequence for the quantification of atherosclerotic plaque components with conventional multi-sequence MRI and histology.
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Eligibility Criteria
Inclusion Criteria:
In order to be eligible to participate in this study, a subject must meet the following criteria:
* Patients with a carotid plaque ≥ 2 mm thick based on ultrasound or CTA
* Age 18 years or older (no maximum age)
* Informed consent by signing informed consent form regarding this…
Inclusion Criteria:
In order to be eligible to participate in this study, a subject must meet the following criteria:
* Patients with a carotid plaque ≥ 2 mm thick based on ultrasound or CTA
* Age 18 years or older (no maximum age)
* Informed consent by signing informed consent form regarding this study
Exclusion Criteria:
A potential subject who meets any of the following criteria will be excluded from participation in this study:
* Patients with carotid plaque ≤ 2 mm in size based on ultrasound or CTA
* Standard contra-indications for MRI (electronic implants like pacemakers or other electronic implants, metallic eye fragments, vascular clips, claustrophobia, etc.)
* Severe co-morbidity, dementia or pregnancy
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