Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease
Recruiting
Observational Study
Liver Cirrhosis
Portal Hypertension
Surgery
Acute-On-Chronic Liver Failure
Non-Cirrhotic Portal Hypertension
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 200 (estimated)
- Sponsor
- University Hospital, Bonn · Other
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About This Trial
Prospective, observational study to define precipitants and predictors of development of Acute-on-Chronic Liver Failure (ACLF) after surgical interventions, allowing to develop a risk stratification for elective procedures in cirrhotic patients. As well as identifying molecular mechanisms of post-interventional ACLF and thus preparing the ground for development of new therapeutic approaches.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Male or female adult (≥18 years) patient
* With or without liver cirrhosis (diagnosed either histologically or by a combination of clinical, laboratory and radiological signs)
* Or Non-cirrhotic portal hypertension
* Non-pregnant, non-lactating females
* Ability to understand …
Contacts