Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth
Recruiting
Observational Study
Transgenderism
Gender Dysphoria
Insulin Sensitivity
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 13 – 16
- Sex
- Any
- Study type
- Observational
- Participants needed
- 90 (estimated)
- Sponsor
- University of Colorado, Denver · Other
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About This Trial
To evaluate the effect of estradiol with or without a prior gonadotropin releasing hormone analogue on insulin sensitivity and vascular function in transgender females compared to cisgender controls.
Trial Locations
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Eligibility Criteria
Inclusion Criteria (transgender females):
* Identify as a transgender female
* Age 13-16 years at the time of enrollment
* If on a gonadotropin releasing hormone analogue, \> 6 months exposure
* Plan to start estradiol clinically in \< 4 months
Inclusion Criteria (cisgender males and females):
* …
Contacts