OSA as a Remote Ischemic Preconditioning in Vascular Surgery
Recruiting
Observational Study
Obstructive Sleep Apnea
Vascular Aneurysm
Ischemia Reperfusion Injury
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic · Other
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About This Trial
Ischemia and reperfusion (I/R) injury during abdominal aortic aneurysm (AAA) repair is inevitable and may lead to postoperative multi-organ failure. Remote ischemic preconditioning (short periods of ischemia in anticipation of longer period of ischemia) may act protectively against ischemia.
Studies of ischemic preconditioning in patients with AAA are conflicting. Obstructive sleep apnea (OSA) is…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* patients scheduled for elective aorto-bifemoral bypass (AAA and Leriche syndrome patients)
Exclusion Criteria:
* emergent surgery
* aorto-bifemoral bypass using deep vein graft
* re-operations
* known OSA with CPAP treatment
Contacts