Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)
Recruiting
Observational Study
NAFLD
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 12 – 18
- Sex
- Any
- Study type
- Observational
- Participants needed
- 260 (estimated)
- Sponsor
- Yale University · Other
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About This Trial
The main aim of the study is to discover the mechanisms underlying the pathophysiology of NAFLD in obese youth.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Good general health, taking no medication on a chronic basis;
* age 12 to 18 years, in puberty (girls and boys: Tanner stage II-V);
* BMI \>85th for obese cohort;
Exclusion Criteria:
* Baseline creatinine \>1.0 mg; pregnancy;
* the presence of endocrinopathies (e.g. Cushing …
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