Localizing Epileptic Networks Using MRI and iEEG
Recruiting
Early Phase 1
Interventional Study
Epilepsy
Epilepsy Intractable
Epilepsy, Temporal Lobe
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 290 (estimated)
- Sponsor
- University of Pennsylvania · Other
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About This Trial
Upon successful completion of this study, the investigators expect the study's contribution to be the development of noninvasive imaging biomarkers to predict IEEG functional dynamics and epilepsy surgical outcomes. Findings from the present study may inform current and new therapies to map and alter seizure spread, and pave the way for less invasive, better- targeted, patient-specific interventio…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients with medication-refractory epilepsy
* Planned intracranial EEG (IEEG) placement
* Hypothesized to have temporal lobe epilepsy
Exclusion Criteria:
* Contraindication to 3T MRI (e.g. metal implants or claustrophobia), clinical features that typically preclude the use …
Contacts