A Clinical Study of MIL95 in Advanced Malignancies.

Recruiting Phase 1 Interventional Study
Advanced Malignancies
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
58 (estimated)
Sponsor
Beijing Mabworks Biotech Co., Ltd. · Industry
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About This Trial
This study is composed of two stages: Part A initial dose escalation and Part B maintenance dose escalation. Both parts will adopt the classical 3+3 dose escalation design. The starting dose for phase Ia part A is 0.1 mg/kg QW, followed by 3 dose cohorts (0.3mg/kg QW, 0.8mg/kg QW and 1mg/kg QW). Duration of dose limiting toxicity (DLT) observation is 14 days. Part B will have 5 dose cohorts(3mg/…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Adult patients, \>=18 years of age; 2. Diagnosis of Refractory/relapsed lymphomas or solid tumor; 3. Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1; 4. Life expectancy \>=3 months; 5. Sufficient organ and bone marrow function; 6. At least one measurabl…
Contacts

Yuqin Song, doctor

(+86)010-88121122

songyuqin622@163.com

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