No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
2,000 (estimated)
Sponsor
University College London Hospitals · Other
Who this trial is looking for
This trial is looking for pregnant women who are at least 18 years old and have concerns about a fetal abnormality, and who decide to proceed with terminating the pregnancy. Participants will provide tissue from developing fetal organs for research purposes.
Are You a Good Fit for This Trial?
You may be able to join if
I am at least 18 years old
I am pregnant
I have concerns about a fetal abnormality
I have decided to proceed with termination of pregnancy
You may not be able to join if
I have tested positive for HIV
I have tested positive for Hepatitis B
I have tested positive for Hepatitis C
I have tested positive for Chlamydia
I have tested positive for Herpes
I am unable to make an informed decision about termination of pregnancy
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Knowledge about abnormal organ development is important to understand pathology and to develop novel treatment approaches for individuals with congenital and acquired disease. Most of our current understanding is based on examination of tissues from the embryo and early fetus, collected from women undergoing termination of pregnancy in the first trimester (third) of pregnancy. There is very little…
Knowledge about abnormal organ development is important to understand pathology and to develop novel treatment approaches for individuals with congenital and acquired disease. Most of our current understanding is based on examination of tissues from the embryo and early fetus, collected from women undergoing termination of pregnancy in the first trimester (third) of pregnancy. There is very little known about normal and abnormal organ development from a developmental perspective during the crucial last two-thirds of pregnancy when much remodelling of fetal tissues occurs. We aim to collect tissue from a variety of developing fetal organs in the last two-thirds of pregnancy from women who decide to undergo a termination of pregnancy and who wish to undergo a clinical fetal postmortem (PM) examination.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* ≥18 years old pregnant women who attend the Fetal Medicine Unit for concerns about a fetal abnormality where they decide to proceed to termination of pregnancy
Exclusion Criteria:
* Screening labs positive for maternal HIV, Hepatitis B and Hepatitis C, Chlamydia and Herpes.
…
Inclusion Criteria:
* ≥18 years old pregnant women who attend the Fetal Medicine Unit for concerns about a fetal abnormality where they decide to proceed to termination of pregnancy
Exclusion Criteria:
* Screening labs positive for maternal HIV, Hepatitis B and Hepatitis C, Chlamydia and Herpes.
* Subject unable to make an informed decision about termination of pregnancy.
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