Polarimetric Colposcopy for Cervical Changes in Pregnancy

Mueller Polarimetric Colposcopy for High-performance Detection of Cervical Changes During Pregnancy

Recruiting N/A Interventional Study
Pregnancy Related Premature Birth
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Female
Study type
Interventional
Purpose
Diagnostic
Participants needed
683 (estimated)
Sponsor
Assistance Publique - Hôpitaux de Paris · Other
Who this trial is looking for

This trial is looking for pregnant women to study cervical changes. Participants will undergo a special examination to evaluate the cervix during their pregnancy.

Are You a Good Fit for This Trial?
Rules you out History of spontaneous premature laborHistory of late miscarriageHistory of premature rupture of membranes

You may be able to join if

  • I am an adult.
  • I have a single pregnancy.
  • I am at least 20 weeks pregnant.
  • I have had an ultrasound in my first trimester.
  • I have given informed consent.

You may not be able to join if

  • I have known or suspected uterine malformation.
  • I have premature rupture of membranes.
  • I have suspicion of chorioamnionitis.
  • I have abundant bleeding that makes it hard to see my cervix.
  • I have a history of conization.
  • I am about to give birth.
  • I do not have social coverage.
  • I have limited understanding.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

Mueller polarimetric colposcopy appears to be a powerful tool for evaluating cervical microstructure modification during pregnancy. Some polarimetric parameters of the uterine cervix can be correlated with the gestational age. The uterine cervix's polarimetric analysis could make it possible to accurately predict the term of childbirth and be used as a screening tool for preterm birth.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Major patient. * Single pregnancy. * Baseline ≥ 20 amenorrhea week for group 1 and baseline ≥ 20 amenorrhea week and \<37 amenorrhea week for group 2. * Dating obtained by ultrasound of the 1st trimester. * Written and informed consent. * Group 1 (low risk): Asymptomatic p…
Contacts

Dominique LUTON, Pr

01 45 21 77 64

dominique.luton@aphp.fr

CONTACT

Angelo PIERANGELO, Dr

01 46 69 43 69

angelo.pierangelo@polytechnique.edu

CONTACT