Adult Pulmonary Langerhans Cell Histiocytosis: a National Registry-based Prospective Cohort Study

Recruiting Observational Study
Histiocytosis Histiocytosis, Langerhans-Cell Histiocytosis Pulmonary
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
500 (estimated)
Sponsor
Assistance Publique - Hôpitaux de Paris · Other
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About This Trial
The long-term outcomes of adult patients with pulmonary Langerhans cell histiocytosis (PLCH), particularly survival, is largely unknown. This is the first prospective study in the field evaluating the long-term outcomes of PLCH patients. This french countrywide registry-based study included a large cohort of PLCH patients followed for a sufficiently long period to address risk factors of long-term…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age \>= 18 years * Diagnosis of PLCH was either histologically confirmed on a biopsy of an involved tissue, or based on the combination of the following criteria: 1) an appropriate clinical picture; 2) a typical nodulo-cystic pattern on lung high-resolution computed tomography…
Contacts

Abdellatif TAZI, MD PhD

142499198

abdellatif.tazi@aphp.fr

CONTACT

matthieu resche-rigon, MD PhD

142499742

matthieu.resche-rigon@u-paris.fr

CONTACT