Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies
Recruiting
Phase 4
Interventional Study
Periodontal Diseases
Antibiotics
Pharmacokinetics
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 45 (estimated)
- Sponsor
- University of Geneva, Switzerland · Other
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About This Trial
Periodontitits is a bacteria induced inflammatory disease that destroys the supporting tissues of the tooth and leads to tooth loss. Treatment consists mainly of the mechanical cleaning of the tooth surfaces in order to remove the bacterial deposits (plaque and calculus). This procedure can reduce the level of pathogenic bacteria but it can not eradicate them. In severe cases, for the complete res…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Informed Consent as documented by signature
* Aged 18-80 years old with need of periodontal treatment associated with adjunctive antibiotic therapy
* Presence of at least 30% of the teeth in the mouth with PD\>6mm and BOP
Exclusion Criteria:
* Persons with systemic illnesses…
Contacts