Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer
Recruiting
N/A
Interventional Study
Lung Cancer
Radiation-Induced Disorder
Radiation Pneumonitis
Pulmonary Disease
Lung Function Decreased
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 90 (estimated)
- Sponsor
- University of Aarhus · Other
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About This Trial
Study aims to determine if functional lung avoidance based on perfusion single photon emission (SPECT)/CT scan, improves toxicity outcomes for patients with advanced lung cancer undergoing chemo-radiotherapy. Functional avoidance implies a dose plan that takes functional distribution in the lung into account, and avoids highly functional lung volumes sparing them from radiation.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* histologically verified lung cancer (small-cell and non-small cell lung cancer)
* referred for radiotherapy with curative intent
* radiation dose of 60-66 Gy given in 2-Gy fractions, other dose levels and fractionation schedules accepted, as per site standard
* concurrent chem…
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