Personalized Protocol for Duodenal and Gastric Polyps in FAP

A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis

Recruiting Observational Study
Familial Adenomatous Polyposis
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
1,000 (estimated)
Sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Other
Who this trial is looking for

This trial is looking for adults diagnosed with familial adenomatous polyposis (FAP). Participants will follow a tailored plan for monitoring and addressing polyps in the stomach and duodenum.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with familial adenomatous polyposis.
  • I am 18 years old or older.

You may not be able to join if

  • I have had all polyps removed endoscopically.
  • I have gastric or duodenal cancer.
  • I need surgery.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

The purpose of this study is to determine the efficacy and safety of a personalized surveillance and intervention protocol for duodenal and gastric polyposis in patients with familial adenomatous polyposis (FAP)

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Diagnosis of FAP, at least one of following: genetic diagnosis (proven APC germline mutation) and/or clinical diagnosis (\>100 colorectal adenomas in combination with a positive family history of FAP) * Age 18 years or older Exclusion Criteria: * Endoscopic removal of all po…
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