Microbiome in Cancer Patients With High Dose Chemotherapy With Stem Cell Transplantation

Recruiting N/A Interventional Study
Hematologic Neoplasms
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
100 (estimated)
Sponsor
National Cancer Institute, Slovakia · Government
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About This Trial
Numerous in vitro and animal studies as well as growing number of clinical studies support the important role of microbiome in carcinogenesis and cancer treatment. Detection of changes in patients´ microbiome following hematopoietic cell transplantation/CAR-T cell therapy and correlations with adverse transplant outcomes, mainly infectious complications, acute and chronic GvHD, disease recurrence …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * signed written informed consent * aged 18 years or older * patients planned to be treated by high-dose chemotherapy and hematopoietic cell transplantation or by CAR-T cell therapy in National Cancer Institute, Slovakia Exclusion Criteria: \- patients not-matching inclusion c…
Contacts

Barbora Kašperová, MD

+421-2-59378272

barbora.kasperova@nou.sk

CONTACT

Sona Ciernikova, PhD

+421-2-59378273

sona.ciernikova@savba.sk

CONTACT