Vitamin C for High Blood Pressure in Obese Adults
Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)
Recruiting
Phase 1
Phase 2
Interventional Study
Hypertension
Cardiovascular Diseases
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 35 – 65
- Sex
- Any
- Trial phase
- Phase 1/2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 23 (estimated)
- Sponsor
- University of Kansas Medical Center · Other
Who this trial is looking for
This trial is looking for obese adults aged 35 to 65 with insulin resistance. Participants will test how Vitamin C impacts their blood vessel health and blood pressure.
Are You a Good Fit for This Trial?
You may be able to join if
- I am obese with a BMI over 30
- I am between 35 and 65 years old
- I can stop taking vitamin C or E supplements and omega-3s for 2 weeks
- I can provide written consent to participate
You may not be able to join if
- I have diabetes with fasting glucose over 126 mg/dL
- I am currently taking a statin or blood pressure medication
- I have high triglycerides over 250 mg/dL
- I have hypertension at levels below 130/80 mmHg
- I have a history of heart disease
- I have a history of vascular disease
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The main purpose of research is to examine and understanding the development of hypertension in obese adults with insulin resistance. Findings from our studies will identify unique mechanisms that can be targeted to limit increases in vascular dysfunction and reduce the excessively high prevalence of hypertension and risk for cardiovascular disease (CVD).
This study is testing the health of the b…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Obese: BMI \>30 m/kg2
2. Middle-aged: 35-65 years
3. Participants must be willing and able to discontinue taking any vitamin C or E supplements or omega-3 fatty acids beginning 2 weeks prior.
4. Able and willing to provide written informed consent
Exclusion Criteria:
1. Dia…
Contacts