Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)
Recruiting
Phase 1
Phase 2
Interventional Study
Hypertension
Cardiovascular Diseases
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 35 – 65
- Sex
- Any
- Trial phase
- Phase 1/2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 23 (estimated)
- Sponsor
- University of Kansas Medical Center · Other
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About This Trial
The main purpose of research is to examine and understanding the development of hypertension in obese adults with insulin resistance. Findings from our studies will identify unique mechanisms that can be targeted to limit increases in vascular dysfunction and reduce the excessively high prevalence of hypertension and risk for cardiovascular disease (CVD).
This study is testing the health of the b…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Obese: BMI \>30 m/kg2
2. Middle-aged: 35-65 years
3. Participants must be willing and able to discontinue taking any vitamin C or E supplements or omega-3 fatty acids beginning 2 weeks prior.
4. Able and willing to provide written informed consent
Exclusion Criteria:
1. Dia…
Contacts