Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C-UCB-J PET Study

Recruiting Observational Study
Cocaine Use Disorder Healthy Controls
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
21 – 60
Sex
Any
Study type
Observational
Participants needed
80 (estimated)
Sponsor
Yale University · Other
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About This Trial

The purpose of this research study is to measure synaptic density in the brain comparing individuals with cocaine use disorder to healthy controls.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 21-60 years * Physically healthy by medical history, physical, neurological, ECG and laboratory examinations * For females, a negative serum pregnancy test * For CUD: DSM-5 criteria for Cocaine Use Disorder and positive urine toxicology showing recent use * For HC: Negativ…
Contacts

Marcella Mignosa, MD

203 974 7557

marcella.mignosa@yale.edu

CONTACT