Study on Lung Health in Smokers at Risk for COPD
Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers
Recruiting
Observational Study
Copd
Smoking
Tobacco Use
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 40 – 75
- Sex
- Any
- Study type
- Observational
- Participants needed
- 40 (estimated)
- Sponsor
- University of California, San Francisco · Other
Who this trial is looking for
This trial is looking for smokers between 40 and 75 years old who have not been diagnosed with COPD or asthma. Participants will help researchers understand why some smokers develop COPD while others do not.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 40 to 75 years old.
- I have a history of at least 20 pack-years of smoking.
- I have not been diagnosed with COPD or asthma.
- I have normal lung function test results.
- I have not smoked in the past 12 months.
- I can be in one of two groups based on my lung capacity tests.
You may not be able to join if
- I have used IV drugs or other recreational drugs besides marijuana.
- I have used marijuana more than 400 times in my lifetime or in the past 6 months.
- I cannot walk briskly, run, or pedal on an exercise machine.
- I am pregnant or breastfeeding.
- I have serious heart conditions.
- I have liver cirrhosis.
- I have chronic active Hepatitis B or C.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease that affects only a fraction of those who smoke tobacco. The origin of this variability in susceptibility to develop COPD is unclear, but understanding its underlying biology has important implications for our ability to design suitable preventative and therapeutic strategies for its management. This Department of Defense (DOD…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Ages between 40 to 75 years old.
* History of at least 20 pack-years of smoking.
* No diagnosis of COPD or asthma.
* No spirometric evidence of airflow obstruction as determined by FEV1/FVC ratio ≥0.7.
* FEV1 and FVC \>lower limit of normal.
* Less than 1 pack-year history of …
Contacts