Alpha-Ketoglutarate and Abdominal Aortic Aneurysm Progression and Rupture

Inclusion Criteria: 1. Presence of an infrarenal AAA with a maximum diameter of 39-49 mm; 2. Han nationality; 3. Between 50 years or more, no gender limit; 4. No mental illness; 5. No history of supplement allergy or supplement allergy; 6. Subjects voluntarily participate in this study, sign an informed consent form, have good compliance, and cooperate with follow-up. Exclusion Criteria: 1. Previous infrarenal aortic surgery; 2. Planned major surgery; 3. Known aortic dissection; 4. Have received any other clinical trial treatment within 1 year; 5. Systemic treatment with corticosteroids or other systemic immunomodulatory therapy; 6. Severe infections, including but not limited to infections requiring hospitalization, bacteremia, severe pneumonia, etc.; 7. Known or suspected inherited connective tissue disorder; 8. Calculated creatinine clearance of less than 30 ml/min; 9. Known significant liver disease; 10. Known human immunodeficiency virus infection at the time of screening； 11. Serious concomitant illness associated with life expectancy of less than 2 years； 12. Any other significant and unstable condition that could limit compliance with the trial protocol.