CHronic Nonbacterial Osteomyelitis International Registry
Recruiting
Observational Study
Chronic Nonbacterial Osteomyelitis
Chronic Recurrent Multifocal Osteomyelitis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- Up to 21
- Sex
- Any
- Study type
- Observational
- Participants needed
- 2,000 (estimated)
- Sponsor
- Seattle Children's Hospital · Other
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About This Trial
The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease and the responses of patients to different clinical managements over 10 years.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* \- Age at enrollment is equal to or younger than 21 years of age
* Presence of bone edema on STIR or T2 fat saturation sequence on MRI within 12 weeks of enrollment
* Whole body imaging evaluation (either WB MRI or bone scintigraphy)
* Bone biopsy to exclude infection or malig…
Contacts