The Pericapsular Nerve Block in Total Hip Arthroplasty
Recruiting
Phase 4Interventional Study
Hip OsteoarthritisHip Arthropathy
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 80
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
78 (estimated)
Sponsor
LifeBridge Health · Other
Who this trial is looking for
This trial is looking for patients needing total hip surgery and managing pain. Participants will receive either a pericapsular nerve block or a fascia iliaca nerve block to compare their effectiveness.
Are You a Good Fit for This Trial?
You may be able to join if
I have signed the informed consent form
I am willing to follow all study procedures
I need a primary total hip arthroplasty using the anterior approach
I have an ASA score of 1 to 3
I can be assigned to one of the two nerve block groups
I have not used opioids before the screening
You may not be able to join if
I have a current or past diagnosis of chronic pain
I have been taking opioids for a week or longer
I have ankylosing spondylitis
I am allergic to any medications used in the study
I will need general anesthesia during the surgery
I am receiving another investigational drug for pain
I have any physical or psychological condition that would affect my participation
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
In order to continue progressing towards outpatient total hip arthroplasty (THA), methods to adequately manage postoperative pain is of paramount importance. The purpose of this study is to quantify the effectiveness of the pericapsular nerve block in total hip arthroplasty in comparison to the fascia iliaca nerve block.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Provision of signed and dated informed consent form
* Stated willingness to comply with all study procedures and availability for the duration of the study
* Planned primary total hip arthroplasty with anterior (Smith-Peterson) approach
* ASA score of 1 to 3
* Indicated for on…
Inclusion Criteria:
* Provision of signed and dated informed consent form
* Stated willingness to comply with all study procedures and availability for the duration of the study
* Planned primary total hip arthroplasty with anterior (Smith-Peterson) approach
* ASA score of 1 to 3
* Indicated for one of the two nerve block groups
* Must be opioid naïve at screening as defined by the FDA - According to the Food and Drug Administration, opioid-tolerant patients were those currently receiving or who had previously received 60 mg PO morphine per day, 25 mcg transdermal fentanyl per hour, 30 mg PO oxycodone per day, 8 mg PO hydromorphone per day, 25 mg PO oxymorphone per day, 60 mg PO hydrocodone per day, or an equivalent dose of another opioid for a duration of one week or longer (16)
Exclusion Criteria:
* Current or previous diagnosis of "chronic pain"
* Opioid tolerant at time of screening (for a week or longer, at least 60 mg of morphine daily, or at least 30 mg of oral oxycodone daily, or at least 8 mg of oral hydromorphone daily or an equianalgesic dose of another opioid.)
* Diagnosis of ankylosing spondylitis
* Allergy to any potential medications utilized in any of the two groups
* Conversion of patient to general anesthesia intraoperatively
* Treatment with another investigational drug or other intervention for pain
* Any condition(s) or diagnosis, both physical or psychological, or physical exam finding in the opinion of the investigator that would precludes participation
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