Pre- Vs Postoperative Thromboprophylaxis for Liver Resection
Recruiting
Phase 4
Interventional Study
Liver Cancer
Surgery
Thrombosis, Deep Vein
Embolism, Pulmonary
Bleeding
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 1,012 (estimated)
- Sponsor
- Helsinki University Central Hospital · Other
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About This Trial
Thromboprophylaxis for liver surgery can be commenced either preoperatively or postoperatively. Despite a clear trade-off between thrombosis and bleeding in liver surgery patients, there is no international consensus when thrombosis prophylaxis should be commenced in patients undergoing liver surgery. As far as we know, there are no prospective randomized trials in this field, and current guidelin…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* All patients undergoing liver resection
Exclusion Criteria:
* Patient on anticoagulative medication (heparin, low-molecular weight heparin, warfarin, direct oral anticoagulants) during last month pre-surgery
* Emergency operation (e.g. for trauma or infection)
* Age \< 18 ye…
Contacts