Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD

Recruiting Phase 2 Interventional Study
Age-related Macular Degeneration
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
50 – 85
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
21 (estimated)
Sponsor
Massachusetts Eye and Ear Infirmary · Other
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About This Trial

interventional trial for off label use of high dose atorvastatin 80 mg in intermediate AMD patients and correlate recovery response measured by dark adaptation recovery time with drusen volume reduction measured by SD-OCT

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * All subjects with intermediate AMD diagnosis in one or both eyes will be considered, regardless the severity stage and subtype of disease in the other eye. High-risk iAMD (numerous large, confluent drusen covering ≥ 0.5 disk area, with or without pigmentary changes but having…
Contacts

John B Miller, MD

617-573-3750

John_miller@meei.harvard.edu

CONTACT

Deeba Husain

617-573-3750

Deeba_Husain@meei.harvard.edu

CONTACT