No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
140 (estimated)
Sponsor
University of Alabama at Birmingham · Other
Who this trial is looking for
This trial is looking for people with Parkinson's disease or essential tremor who are getting ready for surgery. Participants will help researchers learn more about brain activity related to non-motor symptoms during surgery.
Are You a Good Fit for This Trial?
You may be able to join if
I am eligible for surgery based on my doctor's review
I have been diagnosed with Parkinson's disease or essential tremor
I have a movement disorder that hasn't responded to medicine
I am willing to participate in the study activities
You may not be able to join if
I cannot provide full and informed consent
I am younger than 18 years old
I am unable to participate in study-related activities
I have a history of stroke or seizures
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders commonly have significant non-motor features also, including depression, cognitive impairment, decreased attention, and slower processing speeds. The investigators are interested in the brain activity a…
The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders commonly have significant non-motor features also, including depression, cognitive impairment, decreased attention, and slower processing speeds. The investigators are interested in the brain activity associated with these symptoms, and perform recordings of the surface of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Eligible for surgery based on multi-disciplinary consensus review
* Have a diagnosis of Parkinson's disease or Essential Tremor
* Have a diagnosis of medically-refractory movement disorder (Parkinson's disease, Essential Tremor, or dystonia)
* Willingness to participate in the…
Inclusion Criteria:
* Eligible for surgery based on multi-disciplinary consensus review
* Have a diagnosis of Parkinson's disease or Essential Tremor
* Have a diagnosis of medically-refractory movement disorder (Parkinson's disease, Essential Tremor, or dystonia)
* Willingness to participate in the paradigms described in the protocol
Exclusion Criteria:
* Inability to provide full and informed consent
* Age younger than 18
* Are not able to participate in study-related activities
* History of prior ischemic/hemorrhagic stroke, subdural hemorrhage, or seizure
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