Ferric Citrate for Chronic Kidney Disease in Children

Ferric Citrate and Chronic Kidney Disease in Children

Recruiting Phase 2 Interventional Study
Chronic Kidney Diseases
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
6 – 18
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
160 (estimated)
Sponsor
University of California, Los Angeles · Other
Who this trial is looking for

This trial is looking for children aged 6 to 18 with chronic kidney disease stages 3-4. Participants will take either ferric citrate or a placebo for 12 months to see how it affects their health.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 6 and 18 years old.
  • I have chronic kidney disease stages 3-4.
  • I have a stable phosphate level of 5.9 mg/dl or lower.
  • I can swallow tablets.
  • I can eat at least two meals a day.
  • I am willing to follow the study's treatment plan.

You may not be able to join if

  • I am currently treated with phosphate binders.
  • I have a history of allergy to any ingredients in the study products.
  • I have current intestinal malabsorption or Crohn's disease.
  • I may start dialysis or get a kidney transplant within 6 months.
  • I have had a solid organ transplant in the past.
  • I am currently pregnant or breastfeeding.
  • I have cystinosis.
  • I have hemochromatosis.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial
We will conduct a 12-month, double-blind, randomized, placebo-controlled trial to assess the effects of therapy with ferric citrate (FC) on changes in intact FGF23 levels (iFGF23, primary endpoint) in 160 pediatric patients (80 in each of the two arms) aged 6-18 years of either sex with chronic kidney disease (CKD) stages 3-4 and age-appropriate normal serum phosphate levels. Participants will be …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Ages 6 to 18 years (inclusive); 2. Estimated Glomerular Filtration Rate (GFR) of 15-59 ml/min per 1.73 m2 by modified Chronic Kidney disease in Children (CKiD) under 25 (U25) formula;56 3. Serum phosphate \<=5.9 mg/dl; 4. Serum ferritin \<500 ng/ml and TSAT \<50%; 5. For thos…
Contacts

JENNY BROOK, MS

310-7943144

jbrook@mednet.ucla.edu

CONTACT

Barbara Gales, RN

310-206-0799

bgales@mednet.ucla.edu

CONTACT