No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 64
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
204 (estimated)
Sponsor
VA Office of Research and Development · Federal
Who this trial is looking for
This trial is looking for veterans who have served since 9/11 and are dealing with issues like PTSD and impulsive aggression. Participants will go through a treatment to help manage their emotions better and potentially prepare them for further PTSD therapy.
Are You a Good Fit for This Trial?
You may be able to join if
I am a veteran who deployed to combat zones since 9/11.
I have been diagnosed with PTSD.
I have acted aggressively at least 3 times in the last month.
My main type of aggression is impulsive.
I allow a family member or roommate to confirm my aggressive acts.
I agree not to change my psychiatric medications during the study.
You may not be able to join if
I have been suicidal with intent to harm myself in the last week.
I have plans to hurt someone.
I cannot complete self-report questionnaires.
I have been diagnosed with bipolar disorder.
I have been diagnosed with a psychotic disorder.
I have changed my psychiatric medications in the past 4 weeks.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
PTSD is one of the most prevalent mental health conditions affecting Veterans who have served since 9/11. Veterans with posttraumatic stress disorder (PTSD) report difficulty controlling impulsive aggression (IA). An inability to manage one's emotions (emotion dysregulation) is an underlying mechanism of IA. Reducing IA and increasing use of PTSD evidence-based psychotherapies are two critical mis…
PTSD is one of the most prevalent mental health conditions affecting Veterans who have served since 9/11. Veterans with posttraumatic stress disorder (PTSD) report difficulty controlling impulsive aggression (IA). An inability to manage one's emotions (emotion dysregulation) is an underlying mechanism of IA. Reducing IA and increasing use of PTSD evidence-based psychotherapies are two critical missions for the Veterans Health Administration. The proposed research supports these missions by comparing a 3- session emotion regulation treatment (Manage Emotions to Reduce Aggression) to a control group in order to determine if MERA can reduce IA and prepare Veterans for PTSD treatment. By enhancing Veterans' abilities to cope with trauma-related emotions and feel equipped to initiate PTSD treatments, this research aims to help Veterans decrease IA and ultimately recover from PTSD.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Male and female Veterans who deployed to combat zones since 9/11.
2. Currently meets criteria for full or subthreshold PTSD, determined by the Clinician-Administered PTSD Scale for DSM-5
3. Engaged in at least 3 self-reported aggressive acts (e.g., yelling, throwing objects, …
Inclusion Criteria:
1. Male and female Veterans who deployed to combat zones since 9/11.
2. Currently meets criteria for full or subthreshold PTSD, determined by the Clinician-Administered PTSD Scale for DSM-5
3. Engaged in at least 3 self-reported aggressive acts (e.g., yelling, throwing objects, hitting objects/people) in the last month, measured by the Overt Aggression Scale
4. Impulsive aggression is his/her primary form of aggression, determined by the Impulsive Premeditated Aggression Scale
5. Each Veteran must allow an independent aggression rater (live-in partner, family member, or roommate above 18 years of age)\] verify the number of aggressive acts, using the Overt Aggression Scale.
6. Agreement not to change psychotropic medications through the duration of the study.
Exclusion Criteria:
1. Currently suicidal with intent of self-harm in the last week.
2. Currently homicidal with plans to hurt a specific person.
3. Unable to complete self-report measures.
4. Meets diagnostic criteria for bipolar disorder or psychotic disorder.
5. Had a psychotropic medication change within 4 weeks prior to the baseline assessment. Veterans receiving general mental health services or engaging in usual care will be allowed to participate.
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