Regional Phenotyping of CF and Non-CF Bronchiectasis
Recruiting
Observational Study
Cystic Fibrosis
Non-CF Bronchiectasis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 5 – 100
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- Children's Hospital Medical Center, Cincinnati · Other
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About This Trial
The Investigators propose to study pediatric subjects who are diagnosed with cystic fibrosis (CF) and patients with non-CF bronchiectasis, with the goal of developing markers of CF lung disease severity, progression, and therapy response. The Investigator's central hypothesis is that image-based markers can forecast pathophysiology prior to spirometric changes.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* CF Patients: Diagnosis of CF based on sweat chloride \>60 mMol/l
* Presence of two disease causing CFTR mutations, or end organ manifestations of disease.
* Age minimum 5 years.
* Care provided by the CCHMC CF Care Center or other regional CF Care Centers if required to achiev…
Contacts