Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ (DCIS)

Recruiting Observational Study
DCIS
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
46 and older
Sex
Female
Study type
Observational
Participants needed
526 (estimated)
Sponsor
Ontario Clinical Oncology Group (OCOG) · Other
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About This Trial

To evaluate whether the combination of clinicopathological factors and the use of the Oncotype DX DCIS score can avoid radiation in women with low risk DCIS who have had breast conserving surgery (BCS)

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Female patient \> 45 years of age with DCIS without microinvasion. 2. Tumour size ≤ 2.5cm. 3. Treated by BCS with clear resection margins ≥ 2 mm or no residual disease on re-excision.\* \* Patients with anterior margins and posterior margins ≥1 mm are eligible. Or if the …
Contacts

Brittany Speller

905-527-2299

spelleb@mcmaster.ca

CONTACT

Daryl Hannah Soloman

905-527-2299

solomd5@mcmaster.ca

CONTACT