MS-NEUROPLAST: Neuroplasticity of Cortical Areas Induced by Cognitive Training in Patients with Multiple Sclerosis

Inclusion Criteria for people with MS: * Male/female patients aged 18 to 65 years at screening * Diagnosis of MS according to the 2017 Revised McDonald criteria * Disability status at screening with an EDSS score of 0 to 6.5 * Relapsing MS and progressive MS as defined by Lublin * Neurologically stable within 1 month prior to screening * Patients receiving the same Disease Modifying Treatment (DMT) for at least 6 months Exclusion Criteria for people with MS: * Patients suspected of not being able or willing to cooperate or comply with study protocol requirements * Patients meeting criteria for other demyelinating diseases of the CNS * Patients with active chronic disease (or stable but treated with immune therapy) of the immune system other than MS * Patients with any other significant CNS disease or serious psychiatric disorder which can interfere with the patient's ability to cooperate or comply with the study procedure * Patients unable or unwilling to undergo MRI scans and EEG Inclusion Criteria for Healthy Controls: • Normal hearing and normal or corrected-to-normal vision Exclusion Criteria for Healthy Controls: * Any diagnosed neurological, mental, developmental, or psychiatric disorder * Unrecovered neurological disorders (i.e., stroke, traumatic brain injury) * Unstable medication within the last 3 months * Intake of central nervous drugs (e.g., antidepressants) * Severe physical disorder * Concurrent participation in another relevant study * Patients unable or unwilling to undergo EEG measurements