Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury
Recruiting
N/A
Interventional Study
Cannabis
HIV
Inflammation
Cognition
Neuroimaging
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 25 – 59
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 220 (estimated)
- Sponsor
- Wake Forest University Health Sciences · Other
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About This Trial
This study applies a hypothesis-driven approach to examine the effects of chronic marijuana use on HIV-associated inflammation and its subsequent impacts on central nervous system function, with the goal of identifying the mechanisms through which cannabinoids modulate neurological disorders and other comorbidities in persons with HIV.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* verified HIV status
* Current marijuana use (MJ+ groups only)
* No current marijuana use (MJ- groups only)
* current engagement in HIV care (HIV+ participants only)
* receipt of cART as first-line of treatment (HIV+ participants only)
* stable cART regimen (HIV+ participants o…
Contacts