No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 50
Sex
Any
Study type
Observational
Participants needed
120 (estimated)
Sponsor
Memorial Sloan Kettering Cancer Center · Other
Who this trial is looking for
This trial is looking for people aged 18 to 50 who have been diagnosed with early onset colorectal cancer. Participants will help researchers understand how cancer treatments like chemotherapy and radiation affect reproductive and sexual health.
Are You a Good Fit for This Trial?
You may be able to join if
I am 18 to 40 years old and female, or 18 to 50 years old and male.
I have been diagnosed with colorectal adenocarcinoma.
I am willing to take part in the informed consent process.
I am eligible for curative treatment for colon or rectal cancer.
I can complete questionnaires about my health.
If I have rectal cancer, I will receive chemotherapy followed by chemoradiotherapy.
You may not be able to join if
I have had prior treatment for this cancer.
I have an active or prior cancer besides this one.
If I am female, I have had my ovaries removed.
I am pregnant or nursing.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this study is to find out how cancer treatments (chemotherapy and/or radiation therapy) affect reproductive and sexual health in people with early onset colorectal cancer. The study researchers will observe and track changes in hormone levels and in sexual and reproductive health in people with early onset colorectal cancer. This information will help researchers know more about how…
The purpose of this study is to find out how cancer treatments (chemotherapy and/or radiation therapy) affect reproductive and sexual health in people with early onset colorectal cancer. The study researchers will observe and track changes in hormone levels and in sexual and reproductive health in people with early onset colorectal cancer. This information will help researchers know more about how cancer treatments affect reproductive and sexual health, including the ability to have children (fertility).
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18-40 years of age and premenopausal (female) or 18-50 years of age (male) at time of diagnosis
* Histologic diagnosis of colorectal adenocarcinoma
* Able and willing to participate in the informed consent process
* Eligible for curative adjuvant or neoadjuvant therapy for col…
Inclusion Criteria:
* 18-40 years of age and premenopausal (female) or 18-50 years of age (male) at time of diagnosis
* Histologic diagnosis of colorectal adenocarcinoma
* Able and willing to participate in the informed consent process
* Eligible for curative adjuvant or neoadjuvant therapy for colon or rectal cancer
* Willing and able to complete protocol questionnaires
* Rectal patients only: Individuals who will be receiving chemotherapy, followed by chemoradiotherapy (ChemoRT)
Exclusion Criteria:
* Prior systemic treatment for this malignancy
* Active or prior secondary malignancy
* History of ovarian resection (if female)
* Pregnant or nursing (lactating) women, where pregnancy is defined as the state of a female after conception until the termination of gestation, confirmed by a positive hCG laboratory test.
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