Randomized Controlled Trial- Ablation Strategy for Paroxysmal Atrial Fibrillation - Trigger and Substrate Guided Wide Area Radiofrequency Ablation Compared to Pulsed Field Ablation Pulmonary Vein Isolation
Recruiting
N/A
Interventional Study
Atrial Fibrillation
Catheter Ablation
Radiofrequency Catheter Ablation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 556 (estimated)
- Sponsor
- Ottawa Heart Institute Research Corporation · Other
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About This Trial
Atrial fibrillation (AF) is a common heart rhythm disorder affecting over a million people in North America and is associated with serious complications including stroke, heart failure, reduced quality of life, and premature death. Catheter ablation has been shown to be more effective than medications for controlling symptoms and reducing the risk of these complications; however, recurrence of AF …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age ≥18 years on the date of consent for the trial.
2. Subjects must have paroxysmal AF with at least one episode of AF over the past 12 months (patients on antiarrhythmic medications do not need to satisfy this criterion).
At least one episode of AF documented on 12-lead…
Contacts