No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
5 – 21
Sex
Any
Study type
Observational
Participants needed
90 (estimated)
Sponsor
Children's National Research Institute · Other
Who this trial is looking for
This trial is looking for children ages 5 and older who have been diagnosed with juvenile idiopathic arthritis, systemic lupus erythematosus, or fibromyalgia. Participants will be monitored for one year, with their pain and treatment effects assessed regularly without changing their current treatments.
Are You a Good Fit for This Trial?
You may be able to join if
I am 5 years old or older.
I have been diagnosed with juvenile idiopathic arthritis.
I have been diagnosed with systemic lupus erythematosus.
I have been diagnosed with fibromyalgia.
You may not be able to join if
I have a history of eye disease that prevents pupillometry.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The overarching goal of this study is the development of a physiologic endpoint of pain and treatment effect in three distinct rheumatology populations. This would enable objective assessment of pain and treatment in these populations and enable a much more precise approach to treatment. Such an endpoint stands to significantly improve outcomes in these patients by eliminating the need for a trial…
The overarching goal of this study is the development of a physiologic endpoint of pain and treatment effect in three distinct rheumatology populations. This would enable objective assessment of pain and treatment in these populations and enable a much more precise approach to treatment. Such an endpoint stands to significantly improve outcomes in these patients by eliminating the need for a trial-and-error approach to treatment. This is a single site observational study that aims to collect initial pilot data in three distinct patient groups. As this is observational, there is no randomization or blinding in the study. Patients will be followed for a period of one year after enrollment. Baseline measurements will be taken at the time of enrollment, and at each subsequent standard of care clinic visit as feasible, for a period of one year. As this is an observational study, there will be no change to the treatment for any patient due to research activities. The primary objective of this study is the characterization of the nociceptive index in three pediatric rheumatology populations. The secondary objective is the characterization of the nociceptive index in these populations in response to standard of care interventions. This is necessary to demonstrate the ability of this approach to serve as an endpoint of treatment effect.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
In order to be eligible for inclusion in the study, an individual must meet all of the following criteria:
* Male or female ≥ 5 years of age at screening.
* Documentation of a JIA, SLE or FM diagnosis as evidenced by history
Exclusion Criteria:
Any individual who meets any of…
Inclusion Criteria:
In order to be eligible for inclusion in the study, an individual must meet all of the following criteria:
* Male or female ≥ 5 years of age at screening.
* Documentation of a JIA, SLE or FM diagnosis as evidenced by history
Exclusion Criteria:
Any individual who meets any of the following criteria will be excluded from participation in this study:
• Documented history of eye disease precluding pupillometry
Contacts
No contact information available.
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