Weight Loss Surgery and Hysterectomy for Obese Women

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

Recruiting N/A Interventional Study
Endometrial Carcinoma Obesity EIN Endometrial Intraepithelial Neoplasia Endometrial Cancer Stage I
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Female
Study type
Interventional
Purpose
Health Services Research
Participants needed
30 (estimated)
Sponsor
Dana-Farber Cancer Institute · Other
Who this trial is looking for

This trial is looking for women with obesity and endometrial cancer or a related condition. Participants will undergo weight loss surgery and a hysterectomy within a few weeks of their first appointment.

Are You a Good Fit for This Trial?
Rules you out Active smokingSubstance abuseBulimia nervosaSevere psychiatric illnessRecent suicide attemptLarge abdominal herniasPrior bariatric surgery

You may be able to join if

  • I am a woman at least 18 years old
  • My BMI is between 35 and 39.99 and I have a severe obesity-related health issue
  • My BMI is 40 or higher
  • I have a tissue diagnosis of grade 1 endometrial carcinoma or EIN

You may not be able to join if

  • I am younger than 18 years old
  • My BMI is less than 35
  • I do not have a tissue diagnosis, or I have grade 2 or greater endometrial cancer
  • I am currently pregnant
  • I have been advised against bariatric surgery for any reason
  • I cannot read an English consent form
  • I am not willing to provide informed consent

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

To assess the feasibility of an expedited referral process for the obese endometrial cancer or EIN patient from her gynecologic oncologist to the Brigham Center for Metabolic and Bariatric Surgery (CMBS) in order to undergo concurrent weight loss surgery and hysterectomy within 8 weeks of first appointment with a gynecologic oncologist (or 12 weeks for EIN patients).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Female adults at least 18 years of age * A BMI of 35-39.99 and 1 or more severe obesity-related co-morbidities --including T2D,112 hypertension, hyperlipidemia, obstructive sleep apnea (OSA), obesity-hypoventilation syndrome (OHS), Pickwickian syndrome (a combination of OSA…
Contacts

Colleen Feltmate, MD

617-732-8840

cfeltmate@bwh.harvard.edu

CONTACT