Evaluation of Cortisol and Bile Acids Metabolism in Obese Patients
Recruiting
Observational Study
Obesity
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Female
- Study type
- Observational
- Participants needed
- 30 (estimated)
- Sponsor
- University Hospital, Lille · Other
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Bariatric surgery is currently the most efficient treatment for obesity. The sustained weight loss and metabolic improvement seen following Roux-en-Y gastric bypass (RYGB), is explained partly by modifications in hormones including bile acids (BA). After RYGB, an increased total BA pool and a reduction in hepatic cortisol exposure is observed. Hydroxysteroid 11-β dehydrogenase 1 (HSD11B1), steroid…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
* Non-menopausal women
* BMI between 35 and 50 kg/m² included
* Social insured
* Ability to give consent
Exclusion Criteria:
* moderate and severe kidney insufficiency
* hepatic insufficiency
* known gallbladder lithiasis
* history of cholecystectomy or cholecystectomy planned…
Contacts