Impact of ExtraCorporeal Phototherapy (ECP) on Auxiliary Follicular T-lymphocytes and Circulating B-lymphocytes During Chronic AntiBody-Mediated Rejection in Kidney Transplantation.

Recruiting N/A Interventional Study
Kidney Transplantation
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
30 (estimated)
Sponsor
University Hospital, Angers · Government
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About This Trial
Chronic AntiBody-Mediated Rejection (cABMR) is the leading cause of late kidney transplant loss (after 1 year of kidney transplantation). Its therapeutic management is poorly codified and there is currently no treatment referring. Extracorporeal phototherapy (ECP) is a therapeutic apheresis that involves purifying mononucleated cells in the blood, exposing them to UltraViolet A (UVA) and re-injec…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * ECP treatment decision based on transplant team habits (care management) * Age ≥ 18 years * Affiliation to a French social security scheme * Kidney transplant at least 6 months prior to inclusion * cABMR proven by a renal graft biopsy less than 3 months and meeting the followi…
Contacts

Jean-François AUGUSTO, Pr

+33 2 41 35 50 63

JFAugusto@chu-angers.fr

CONTACT

Emma BLANCHET

+33 2 41 35 63 38

EmBlanchet@chu-angers.fr

CONTACT