MicroRNA Correlates of Childhood Maltreatment and Suicidality

Recruiting Observational Study
Major Depressive Disorder Suicidal Ideation
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 60
Sex
Any
Study type
Observational
Participants needed
450 (estimated)
Sponsor
University of Alabama at Birmingham · Other
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About This Trial
This is a research study to find out if childhood trauma and stress are associated with depression or suicidal risk. The study will assess the effects of both short-term and long-term stress on biomarker (e.g. miRNA \[MiRNA\]) levels. miRNAs are a type of RNA (genetic material that is translated into protein) that are found in throughout the body and blood. They are called microRNA because their s…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age 18-60 2. Physically healthy 3. Willing and able to provide informed consent 5\. Diagnosis of MDD or No history of mental illness Exclusion Criteria: 1. Pregnancy or lactation (women of reproductive potential must have a negative urine pregnancy screen) 2. Post-partum s…
Contacts

Allison Stewart, BA

256-551-4428

allisonstewart@uabmc.edu

CONTACT

Richard C Shelton, MD

256-551-6630

rcshelton@uabmc.edu

CONTACT