Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease
Recruiting
N/A
Interventional Study
Schizophrenia
Bipolar Disorder
Alzheimer Disease
FTD
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 45 – 80
- Sex
- Any
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 120 (estimated)
- Sponsor
- Hôpital le Vinatier · Other
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About This Trial
The validation of biomarkers allowing the discrimination of cognitive and behavioral disorders of psychiatric origin from those of neurodegenerative origin would facilitate diagnosis and improve patient management. Neurofilaments, which are markers of neuronal lysis, appear to be a promising biomarker. In a previous preliminary study, the investigators demonstrated significantly lower concentratio…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* haven given written consent
Participants with psychiatric conditions:
* Schizophrenia (DSM-V criteria) with or without cognitive involution
* Bipolar disorder (DSM-V criteria) with or without cognitive involution
Participants with neurodegenerative disease:
* probable or d…
Contacts