Safety of Splenic Stimulation for RA

Recruiting N/A Interventional Study
Rheumatoid Arthritis
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
22 – 75
Sex
Any
Study type
Interventional
Purpose
Device Feasibility
Participants needed
5 (estimated)
Sponsor
Galvani Bioelectronics · Industry
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About This Trial
This study will evaluate the safety and tolerability of stimulating the splenic neurovascular bundle (NVB) with the Galvani System, which consists of a lead, implantable pulse generator, external components and accessories. Participants eligible for implant will have active rheumatoid arthritis (RA) and have an inadequate response or intolerance to at least two biologic Disease Modifying Anti-Rheu…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adult-onset RA of at least six months duration * Male or female participants, 22-75 years of age * Active RA * Inadequate Response to at least 2 biologic DMARDs and/or JAK- inhibitors (JAKis) * Have an appropriate washout from previously used biological DMARDs or JAKi * A fema…
Contacts

Operations Director

+44 (0)800 3688514

clinical@galvani.bio

CONTACT