Classic vs Deep rTMS for Treatment-Resistant Depression
Effects of a Classic High-frequency rTMS Treatment Versus a Deep rTMS Treatment
Recruiting
N/A
Interventional Study
Depressive Disorder, Treatment-Resistant
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 152 (estimated)
- Sponsor
- Centre Hospitalier Henri Laborit · Other
Who this trial is looking for
This trial is looking for adults with treatment-resistant depression to compare two types of brain stimulation treatments. Participants will receive either classic or deep rTMS treatment along with standard therapy, with a total of 20 sessions planned over several weeks.
Are You a Good Fit for This Trial?
You may be able to join if
- I am over 18 years old
- I have signed a consent form
- I have been diagnosed with depressive disorder
- I have not changed my antidepressant treatment in 3 weeks
- I have a MADRS score of 21 or higher
- I am affiliated with a social security regimen
You may not be able to join if
- I have depression with psychotic features
- I have had schizophrenia or a substance abuse problem
- I have already received seismotherapy for my current depression
- I am under hospitalization or legal protection
- I am at high risk of suicide without hospitalization
- I have a personal history of seizures or serious neurological issues
- I am pregnant
- I am participating in another intervention study
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
The main objective is to demonstrate that dTMS is more efficient than high frequency rTMS with a conventional coil.
The patient will receive treatment arm A or B :
Arm A : classic rTMS treatment (use of the 8-shaped coil) and standard therapy Arm B: treatment with deep rTMS (use of the H-shaped coil (helmet)) and standard therapies.
20 rTMS sessions are planned (5 sessions per week) and 3 follo…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Volunteer subjects over 18 years old
* Having signed a free and informed consent
* Having a diagnostic of caracterised depressive episod recurrent or isolated according to DSM IV criteria (A.P.A 1994).
* Having an antidepressant treatment not modified since 3 weeks
* Score to …
Contacts