Comparison of RCA and RACD in Extra-renal Purification by SLED
Recruiting
N/A
Interventional Study
Acute Kidney Injury
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Health Services Research
- Participants needed
- 138 (estimated)
- Sponsor
- Groupe Hospitalier Sud Ile-de-France · Other
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About This Trial
One of the main RRT issues is anticoagulation of the ECC, because blood contact with biomaterials causes bio-incompatibility reactions, including activation of the coagulation cascade. Based on Regional Citrate Anticoagulation (RCA) protocols, an ionized calcium (Ca-ion) concentration around 0.25 to 0.35mmol / L prevents fibrino formation and allows anticoagulation for the ECC. During RCA, metabol…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* All patient requiring Renal replacement Therapy
Exclusion Criteria:
* Age \< 18 years
* Pregnancy
* Hypercalcemia ≥ 3 mmol/L.
* Major under guardianship
* Major deprived of freedom
* Impossible to obtain free and informed consent
* Presence of hemostasis or coagulation disor…
Contacts
No contact information available.