No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
50 – 85
Sex
Any
Study type
Interventional
Purpose
Screening
Participants needed
820 (estimated)
Sponsor
Baker Heart and Diabetes Institute · Other
Who this trial is looking for
This trial is looking for people over 50 who have survived COVID-19. Participants will help researchers learn about exercise programs and medical treatments for improving heart health.
Are You a Good Fit for This Trial?
Must not be takingACE inhibitorsBeta blockers
You may be able to join if
I have a history of COVID-19 infection
I live in a location that is easy to reach for follow-up
You may not be able to join if
I have severe heart valve problems
I have had heart failure before
I cannot get clear images from heart tests
I cannot take beta blockers or ACE inhibitors
I have a life expectancy of less than 12 months
I cannot exercise due to mobility issues
I cannot give written consent to join this study
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This is a prospective study in which a process of identifying and improving a reduction of functional capacity in COVID-19 survivors \>50 years old.
The overall goal of this study to identify the feasibility and value of risk-guided medical therapy and exercise intervention in COVID-19 survivors.
Trial Locations
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City
State
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Status
Eligibility Criteria
Inclusion Criteria:
1. History of COVID-19 infection
2. Live within a geographically accessible area for follow-up
Exclusion Criteria:
1. Valvular stenosis or regurgitation of \>moderate severity
2. History of previous heart failure (baseline New York Heart Association (NYHA) classification \>2)
…
Inclusion Criteria:
1. History of COVID-19 infection
2. Live within a geographically accessible area for follow-up
Exclusion Criteria:
1. Valvular stenosis or regurgitation of \>moderate severity
2. History of previous heart failure (baseline New York Heart Association (NYHA) classification \>2)
3. Inability to acquire interpretable images (identified from baseline echo)
4. Contraindications to beta blockers or angiotensin-converting enzyme inhibitors
5. Oncologic (or other) life expectancy \<12 months or any other medical condition (including pregnancy) that results in the belief (deemed by the Chief Investigators) that it is not appropriate for the patient to participate in this trial
6. Already taking both angiotensin converting enzyme inhibitors/ angiotensin receptor blockers and beta blockers, or intolerance (or allergy) to both.
7. Mobility impairment that would impact participants' ability to perform exercise
8. Unable to provide written informed consent to participate in this study
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