MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

Recruiting N/A Interventional Study
Alcohol Use Disorder Alcohol Drinking Substance Use Drinking, Alcohol Alcohol Use Disorder (AUD)
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
21 – 65
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
86 (estimated)
Sponsor
Medical University of South Carolina · Other
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About This Trial
The purpose of this study is to develop transcranial magnetic stimulation (TMS), specifically TMS at a frequency known as theta burst stimulation (TBS), to see how it affects the brain and changes the brain's response to alcohol-related pictures. TMS and TBS are stimulation techniques that use magnetic pulses to temporarily excite specific brain areas in awake people (without the need for surgery,…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 21-65 (to maximize participation; note: Scalp-to-Cortex distance will be included as a covariate to calculate adjusted TMS dose given expected cortical atrophy in heavy alcohol users and older adults and the demonstrated effect50 on TMS-fMRI responses in addiction) * Alcoh…
Contacts

Lisa M McTeague

842-792-8274

mcteague@musc.edu

CONTACT

Rhia Walton

842-792-8274

waltonrh@musc.edu

CONTACT