Opioid/Benzodiazepine Polydrug Abuse: Aim 3
Recruiting
Phase 2
Interventional Study
Opioid Abuse
Benzodiazepine Abuse
Polysubstance Abuse
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 24 (estimated)
- Sponsor
- Wayne State University · Other
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About This Trial
In this study, the investigators will measure affective, neurocognitive and behavioral outcomes related to chronic use of opioids and benzodiazepines (screening phase), and in response to the administration of the opioid morphine, the benzodiazepine alprazolam, morphine then alprazolam, alprazolam then morphine, morphine+alprazolam simultaneously, and placebo (laboratory pharmacology experiment). …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* must self-report past 10-year experience taking opioid and sedative drugs (for therapeutic or non-therapeutic reasons), but not necessarily at the same time. As an alternative to the sedative drug exposure requirement, participants must have used alcohol on at least 3 separate…
Contacts