No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Pivotal Trial
This treatment is in the last trial phase before FDA approval.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Prevention
Participants needed
600 (estimated)
Sponsor
Alliance for Clinical Trials in Oncology · Other
Who this trial is looking for
This trial is looking for rural cancer survivors who smoke and want to quit. Participants will receive support through a text-based program designed to help reduce smoking.
Are You a Good Fit for This Trial?
Must not be takingNicotine replacement therapyBupropionVarenicline
You may be able to join if
I have been diagnosed with cancer within the past 10 years.
I smoke at least 5 cigarettes a day.
I live in a rural area.
I am interested in joining a program to stop smoking.
I can speak and read English or Spanish.
I am at least 18 years old.
I have a smartphone with texting ability.
I am willing to provide a urine sample.
You may not be able to join if
I am currently receiving hospice care.
I only vape and do not smoke cigarettes.
I am using smoking cessation medications.
I am currently in another smoking cessation clinical trial.
I have impaired decision-making capacity.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This phase III trial compares the effect of text-based cessation intervention to a manual in helping rural cancer patients who smoke, quit. Text-based scheduled gradual reduction may reduce the frequency of cigarette use to zero and may be effective in quitting smoking.
Trial Locations
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Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
* Have a cancer diagnosis within the past 10 years
\* Note: Patients with ductal carcinoma in situ (DCIS) are eligible and patients currently receiving curative treatment are eligible
* Not currently on hospice
* Currently smokes \>= 5 cigarettes daily
\* Note: Participant…
Inclusion Criteria:
* Have a cancer diagnosis within the past 10 years
\* Note: Patients with ductal carcinoma in situ (DCIS) are eligible and patients currently receiving curative treatment are eligible
* Not currently on hospice
* Currently smokes \>= 5 cigarettes daily
\* Note: Participants who smoke cigarettes and vape are eligible. Those who only vape are ineligible
* Lives in a nonmetro/rural county (defined as having a Rural Urban Continuum Code \[RUCC\] code of 4-9) and/or a Rural-Urban Commuting area code of 4-10 and/or as defined by the Office of Management and Budget as a non-rural county large area metro census tracts of at least 400 square miles in an area with population density of 35 or less per square mile with rural-urban commuting area (RUCA) codes 2-3; and outlying metro counties without a UA. The RUCC code and RUCA (4-10) codes can be checked at: https://www.ruralhealthinfo.org/am-i-rural. Those with RUCA codes of 2-3 can be checked at https://data.hrsa.gov/tools/rural-health for eligibility
* Patient interested in participating in a smoking cessation program, and not currently participating in a smoking cessation clinical trial
* Not currently using any smoking cessation pharmacotherapy (e.g. nicotine replacement therapy, bupropion or varenicline for smoking purposes only), or currently participating in any cessation program at the time of enrollment
* Patient has a cell phone or smart phone device with texting ability
* In order to complete the mandatory patient-completed measures, participants must be able to speak and read English or Spanish
* Age \>= 18 years
* Participant must be willing to provide a urine sample.
* Patients with impaired decision-making capacity are not eligible for this study consent
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