Donepezil and Cognitive Training for Alcohol Use Disorder (AUD)

Recruiting Phase 2 Interventional Study
Alcohol Use Disorder
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 80
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
160 (estimated)
Sponsor
VA Connecticut Healthcare System · Federal
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About This Trial

The goal of the project is to evaluate whether donepezil + cognitive remediation therapy is superior to placebo in reducing heavy drinking in patients with alcohol use disorder in a double-blind, placebo-controlled trial.

Trial Locations
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Eligibility Criteria
Inclusion criteria: 1. Males and females 18-80 years of age 2. Fluency in English and a 6th grade or higher reading level 3. Meets the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for a current alcohol use disorder (subjects should have a primary alcohol use disorder \[AUD…
Contacts

Gihyun Yoon, MD

203-932-5711

gihyun.yoon@yale.edu

CONTACT