Effect of Early Administration of TXA in Adult Hip Fractures

Recruiting Phase 2 Phase 3 Interventional Study
Postoperative Blood Loss
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2/3
Study type
Interventional
Purpose
Prevention
Participants needed
170 (estimated)
Sponsor
Ascension Health · Industry
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About This Trial
This is a prospective clinical study designed to assess blood loss in intracapsular and extracapsular hip fractures undergoing operative fixation at a Level II trauma center. It is well established in the orthopedic literature that tranexamic acid (TXA) decreases blood loss and need for postoperative blood transfusion in hip fracture patients as well as total joint arthroplasty patients. A typical…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * 1\. All adult (18 years old or older) hip fracture patients presenting with an acute hip fracture and undergoing operative fixation Exclusion Criteria: 1. Polytrauma patients 2. Previous operation on the ipsilateral hip 3. Patients with coagulopathies (Factor V Leiden, Sickl…
Contacts

Jacob Hinkley, DO, MS

810-606-5669

jacob.hinkley2@ascension.org

CONTACT

Jacob Lytle, DO

810-606-5669

jacob.lytle@ascension.org

CONTACT